USP22

Description		ubiquitin specific peptidase 22
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Cytoplasm Transcription Factor TFTC Complex
	Molecular Function	Transcription Coactivator Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Histone H4 Acetyltransferase Activity Hydrolase Activity Enzyme Binding Metal Ion Binding Histone H2B Deubiquitinase Activity Histone H2A Deubiquitinase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of DNA Repair Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Proteolysis Embryo Development Ending In Birth Or Egg Hatching Protein Deubiquitination Positive Regulation Of Type I Interferon Production Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription Positive Regulation Of Mitotic Cell Cycle
Pathways		HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mosquito bite size ( 28199695)
Novel Interacting Genes		1 novel interacting genes: B9D1
Interacting Genes		17 interacting genes: BAG4 CEBPA H2AC20 H2AC4 H2BC21 H2BC3 HEXA MRPL10 MRPL44 MTUS2 PALB2 PSME1 PTGS2 RCAN1 SCFD1 UBC ZEB1
Entrez ID		23326
HPRD ID		19411
Ensembl ID		ENSG00000124422
Uniprot IDs		Q9UPT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Heterodimerization Activity Structural Constituent Of Chromatin Nucleosome
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