TRIM2

Gene Name		tripartite motif containing 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Protein Ubiquitination Regulation Of Neuron Apoptotic Process
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS		Multiple sclerosis ( 21654844)
Protein-protein Interactions		23 interactors: BCL2L11 CIB3 DTNBP1 GJB5 MNAT1 MYO5A OTUB2 SIRPA TNFAIP3 TNIK TRIM8 UBAC1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2U UBE2W
Entrez ID		23321
HPRD ID		10279
Ensembl ID		ENSG00000109654
Uniprot IDs		Q9C040
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Cellular Protein Modification Process Cellular Protein Metabolic Process Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Response To Stress Cellular Macromolecule Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Response To Stress Proteolysis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K63-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Protein Monoubiquitination Activation Of Innate Immune Response Catabolic Process ISG15-protein Conjugation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Innate Immune Response Protein K11-linked Deubiquitination TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Regulation Of Innate Immune Response Cellular Response To DNA Damage Stimulus Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein K48-linked Deubiquitination Negative Regulation Of Protein Ubiquitination Protein K63-linked Deubiquitination Toll-like Receptor Signaling Pathway Regulation Of Cell Cycle Cellular Response To Oxygen Levels Cellular Response To Organic Substance Pigmentation Cellular Metabolic Process Response To Stimulus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		acc adenoid aetiology bbc col9a3 constitutes driver drivers foxa1 gpm6b insidious lacks massive mel metastasise metastasises mia myoepithelial neuroblastomaand oestrogen recur ropn1 ropn1b segregated shares signatures silico sox10 visualisation