DMXL2

Description		Dmx like 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle RAVE Complex Synapse Neuronal Dense Core Vesicle
	Molecular Function	Small GTPase Binding
	Biological Process	Vacuolar Acidification
Pathways
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) C-reactive protein levels ( 30388399) Intelligence (MTAG) ( 29326435) Triglyceride levels ( 32203549)
Interacting Genes		5 interacting genes: AKTIP ETS2 MTNR1B PCNT RAB3A
Entrez ID		23312
HPRD ID		10188
Ensembl ID		ENSG00000104093
Uniprot IDs		H0YLM8 Q8TDJ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Ectodermal Cell Fate Commitment Melatonin Receptor Activity Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Constitutive Secretory Pathway Synaptic Vesicle Maturation Regulation Of Presynaptic Dense Core Granule Exocytosis Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Regulation Of Plasma Membrane Repair Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Acrosomal Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Regulation Of Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Maintenance Of Presynaptic Active Zone Structure Clathrin-sculpted Monoamine Transport Vesicle Membrane Sensory Perception Of Touch FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Primitive Streak Formation Cell Fate Commitment Involved In Formation Of Primary Germ Layer Nuclear Glucocorticoid Receptor Binding Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Trans-synaptic Signaling Synaptic Signaling Chemical Synaptic Transmission Vesicle Organization Synaptic Vesicle Clustering Regulation Of Short-term Neuronal Synaptic Plasticity Presynaptic Active Zone Organization Positive Regulation Of Protein Binding HOPS Complex Negative Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Plasma Membrane Organization Myosin V Binding Synaptic Vesicle Recycling Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Nervous System Process Regulation Of Circadian Sleep/wake Cycle, Sleep Ubiquitin-like Protein Transferase Activity Positive Regulation Of Circadian Rhythm Regulation Of Protein Transport GTP-dependent Protein Binding
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