TASOR

Description		transcription activation suppressor
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GO Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	Chromatin Binding RNA Binding Protein Binding
	Biological Process	Anterior/posterior Axis Specification, Embryo Negative Regulation Of Gene Expression, Epigenetic Mesodermal To Mesenchymal Transition Involved In Gastrulation Protein Localization To Heterochromatin Constitutive Heterochromatin Formation Transposable Element Silencing By Heterochromatin Formation
Pathways		Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		5 interacting genes: AP2M1 RB1 RNF10 TBC1D4 TOM1L1
Entrez ID		23272
HPRD ID		10183
Ensembl ID		ENSG00000163946
Uniprot IDs		Q9UK61
PDB IDs		6SWG 6TL1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glial Cell Proliferation Disordered Domain Specific Binding Negative Regulation Of Gliogenesis Regulation Of Glial Cell Proliferation Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Cellular Component Organization Positive Regulation Of Synaptic Vesicle Recycling Postsynaptic Neurotransmitter Receptor Internalization Signal Sequence Binding Extrinsic Component Of Presynaptic Endocytic Zone Membrane Regulation Of Gliogenesis Negative Regulation Of Cell Cycle Process Negative Regulation Of Myofibroblast Differentiation Sister Chromatid Biorientation Negative Regulation Of Nervous System Development Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity Regulation Of Mitotic Nuclear Division Regulation Of Myofibroblast Differentiation Negative Regulation Of Hepatocyte Apoptotic Process Enucleate Erythrocyte Differentiation Cellular Response To Insulin Stimulus Glial Cell Apoptotic Process Regulation Of Nuclear Division Negative Regulation Of Mitotic Cell Cycle Response To Insulin Negative Regulation Of Cell Development Rb-E2F Complex Regulation Of Protein Kinase Activity Regulation Of Centromere Complex Assembly Cellular Response To Peptide Hormone Stimulus Regulation Of Collagen Fibril Organization Cyclin/CDK Positive Transcription Elongation Factor Complex Regulation Of Kinase Activity Chromatin Lock Complex Importin-alpha Family Protein Binding Negative Regulation Of Neurogenesis Positive Regulation Of Collagen Fibril Organization Negative Regulation Of Vesicle Fusion Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Positive Regulation Of Protein Autophosphorylation AP-2 Adaptor Complex Positive Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Organelle Organization Response To Peptide Hormone Clathrin Adaptor Complex Cellular Response To Hormone Stimulus
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