FMO1

Description		flavin containing dimethylaniline monoxygenase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Oxidoreductase Activity Trimethylamine Monooxygenase Activity Hypotaurine Monooxygenase Activity Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Organic Acid Metabolic Process Xenobiotic Metabolic Process Toxin Metabolic Process Response To Lipopolysaccharide Taurine Biosynthetic Process Negative Regulation Of Fatty Acid Oxidation Energy Homeostasis
Pathways		Degradation of cysteine and homocysteine FMO oxidises nucleophiles
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Sudden cardiac arrest ( 21658281) Type 2 diabetes (age of onset) ( 28060188)
Novel Interacting Genes		1 novel interacting genes: FLT3
Interacting Genes		7 interacting genes: CREB3 GRINA LEPROTL1 REEP4 SLC10A6 SLC71A2 TLN1
Entrez ID		2326
HPRD ID		00631
Ensembl ID		ENSG00000010932
Uniprot IDs		B2RCG5 Q01740
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Deacetylase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Membrane Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
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