PACS2

Gene Name		phosphofurin acidic cluster sorting protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function
	Biological Process	Autophagic Vacuole Assembly Apoptotic Process Viral Process Protein Localization To Pre-autophagosomal Structure Protein Targeting To Plasma Membrane
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: BIRC2 BIRC3 PKD2 TRAF2
Entrez ID		23241
HPRD ID		17816
Ensembl ID		ENSG00000179364
Uniprot IDs		E9PB38 G8JLK3 Q86VP3 Q8N7J0
PDB IDs
Enriched GO Terms of Interacting Partners?		NIK/NF-kappaB Signaling Programmed Necrotic Cell Death Necrotic Cell Death TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Immune Response-regulating Signaling Pathway Toll-like Receptor Signaling Pathway Positive Regulation Of Immune Response Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Heterooligomerization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Negative Regulation Of Necroptotic Process Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Necrotic Cell Death Positive Regulation Of Innate Immune Response Regulation Of Immune Response Regulation Of RIG-I Signaling Pathway Regulation Of Necroptotic Process Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Cell Death Death Regulation Of Necrotic Cell Death Regulation Of Innate Immune Response Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Necroptotic Process Positive Regulation Of Signal Transduction Regulation Of Immune System Process Positive Regulation Of Interleukin-2 Production Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Protein Oligomerization Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Defense Response To Virus Immune System Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Tagcloud ?		ada3 backbone bak bid conferred cooperatively diablo granzyme hairpin hgrzb kd lentiviral mechanistically mir30 pcaf perforin permeabilization phenocopied pool pores reside screen shrnamir shrnamirs smac tbid toxins transduced unaltered