RHOBTB2

Description		Rho related BTB domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Plasma Membrane Endosome Membrane Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Cell Shape Protein Ubiquitination Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization
Pathways		RHOBTB2 GTPase cycle
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Aspartate aminotransferase levels ( 33547301) Basal cell carcinoma ( 33549134) Height ( 28552196) Plasma trimethylamine N-oxide levels ( 28439531) Renal cell carcinoma ( 28598434) Survival in breast cancer (estrogen-receptor positive) ( 29423119)
Interacting Genes		12 interacting genes: BAG4 CHEK2 CUL5 ERBB2 FGFR2 HSP90AA1 HSP90AB1 PALB2 PPM1D PTPN1 RHOBTB3 STK11
Entrez ID		23221
HPRD ID		06300
Ensembl ID		ENSG00000008853
Uniprot IDs		Q9BYZ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Binding Cellular Response To Stress Response To Stress ATP Binding Regulation Of Intracellular Signal Transduction Macromolecule Metabolic Process Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Telomerase Holoenzyme Complex Assembly Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Protein Localization Protein Metabolic Process Protein Stabilization Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Response To Unfolded Protein Protein Dephosphorylation Cellular Response To Growth Factor Stimulus Protein Modification Process Signal Transduction By P53 Class Mediator Regulation Of Protein Modification Process Growth Hormone Receptor Signaling Pathway Via JAK-STAT Nucleotide Binding Response To Growth Factor Regulation Of Cell Communication Regulation Of Signaling Protein Phosphorylation Protein Autophosphorylation Negative Regulation Of Cell Population Proliferation Dephosphorylation Chaperone-mediated Protein Complex Assembly Telomere Maintenance Via Telomerase Regulation Of Protein Stability DNA Polymerase Binding Phosphorylation ERBB2 Signaling Pathway Growth Hormone Receptor Signaling Pathway Regulation Of Primary Metabolic Process Axonal Growth Cone RNA-templated DNA Biosynthetic Process Mitotic Cell Cycle Phase Transition Phosphate-containing Compound Metabolic Process MHC Class II Protein Complex Binding Disordered Domain Specific Binding Cell Cycle Phase Transition Negative Regulation Of Apoptotic Process Myelin Sheath Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
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