ATG4B

Description		autophagy related 4B cysteine peptidase
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GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Endoplasmic Reticulum Cytosol Cytoplasmic Vesicle
	Molecular Function	Endopeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Protein-phosphatidylethanolamide Deconjugating Activity Scaffold Protein Binding
	Biological Process	Autophagosome Assembly Mitophagy Proteolysis Autophagy Protein Transport Macroautophagy Microautophagy Protein Processing Otolith Mineralization Completed Early In Development Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Aggrephagy Protein Delipidation
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Asthma ( 31959851) Body mass index ( 29273807) Carotid intima media thickness ( 30510157) Crohn's disease ( 26192919) Prostate cancer ( 23535732)
Interacting Genes		5 interacting genes: GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B
Entrez ID		23192
HPRD ID		16499
Ensembl ID		ENSG00000168397
Uniprot IDs		B3KVU2 B7ZA52 Q9Y4P1
PDB IDs		2CY7 2D1I 2Z0D 2Z0E 2ZZP 5LXH 5LXI
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Vacuole Organization Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Autophagy Ubiquitin Protein Ligase Binding GABA Receptor Binding Response To Nutrient Levels Organelle Assembly Beta-tubulin Binding Microtubule Binding Cytoplasmic Vesicle Microtubule Protein-containing Complex Organization Cellular Response To Stress Catabolic Process Endomembrane System Cellular Component Assembly Organelle Organization Organelle Membrane Response To Stress Cytoskeleton Axoneme Positive Regulation Of Protein K48-linked Ubiquitination Cellular Response To Oxygen-glucose Deprivation Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein K48-linked Ubiquitination Response To Iron(II) Ion Ceramide Binding Tat Protein Binding Cytosol Response To Oxygen-glucose Deprivation Glycophagy Autolysosome Golgi Apparatus Regulation Of Protein Catabolic Process Regulation Of Proteolysis Protein Localization To Endoplasmic Reticulum
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