ATG4B

Gene Name		autophagy related 4B, cysteine peptidase
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Endopeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation C-terminal Protein Lipidation Proteolysis Protein Targeting To Membrane Autophagy Cellular Response To Nitrogen Starvation Positive Regulation Of Autophagy Protein Processing Nucleophagy Positive Regulation Of Protein Catabolic Process Protein Delipidation
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-protein Interactions		6 interactors: GABARAP GABARAPL1 GABARAPL2 LINC00341 MAP1LC3A MAP1LC3B
Entrez ID		23192
HPRD ID		16499
Ensembl ID		ENSG00000168397
Uniprot IDs		B3KVU2 F5H7P2 F8WD71 Q9Y4P1
PDB IDs		2CY7 2D1I 2Z0D 2Z0E 2ZZP
Enriched GO Terms of Interacting Partners?		Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Membrane Fusion Cellular Response To Starvation Autophagy Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Mitochondrion Organization Response To Nutrient Levels Cellular Response To Nitrogen Starvation Response To Extracellular Stimulus Organelle Assembly Membrane Organization Cellular Response To Stress Catabolic Process Response To External Stimulus Cellular Component Assembly Organelle Organization Response To Stress Cell Communication Cellular Response To Stimulus Response To Stimulus Positive Regulation Of ATPase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of ATPase Activity Intra-Golgi Vesicle-mediated Transport Negative Regulation Of Proteasomal Protein Catabolic Process Cellular Metabolic Process Negative Regulation Of Cellular Protein Catabolic Process Extrinsic Apoptotic Signaling Pathway
Tagcloud ?		akt1 antipsychotic atg12 atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional gabarap henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask