MLANA

Description		melan-A
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Melanosome Membrane Melanosome
	Molecular Function	Protein Binding
	Biological Process
Pathways		Regulation of MITF-M-dependent genes involved in pigmentation
Drugs
Diseases
GWAS		Asthma ( 31619474 31959851) Hippocampal volume in mild cognitive impairment ( 29274321) Multiple sclerosis ( 22190364)
Novel Interacting Genes		1 novel interacting genes: ERMP1
Interacting Genes		4 interacting genes: EPN2 ITCH NEDD4 YAP1
Entrez ID		2315
HPRD ID		09269
Ensembl ID		ENSG00000120215
Uniprot IDs		A0A384MR46 Q16655
PDB IDs		2GT9 2GTW 2GTZ 2GUO 3HG1 3L6F 3MRO 3MRP 3MRQ 3QDM 3QEQ 3QFD 4EUP 4JFF 4L3E 4QOK 4WJ5 5E9D 5NHT 5NQK 6D78 6DKP 6TMO 7Q9B 7TR4
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Proline-rich Region Binding Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Signal Transduction Receptor Internalization Mesenchyme Development Endocytosis Negative Regulation Of Cell Communication Protein K63-linked Ubiquitination Negative Regulation Of Signaling Protein Monoubiquitination Formation Of Structure Involved In A Symbiotic Process Regulation Of Notch Signaling Pathway Regulation Of Stem Cell Differentiation Enterocyte Differentiation Import Into Cell Intracellular Signal Transduction Negative Regulation Of Cellular Response To Growth Factor Stimulus Channel Inhibitor Activity Cell Cortex Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Cellular Response To Radiation Phosphothreonine Residue Binding Receptor-mediated Endocytosis Lateral Mesoderm Development TEAD-YAP Complex Cardiac Muscle Tissue Regeneration T Cell Anergy Phosphoserine Residue Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Beta-2 Adrenergic Receptor Binding Positive Regulation Of Protein Catabolic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Developmental Process Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Positive Regulation Of T Cell Anergy CXCL12-activated CXCR4 Signaling Pathway T Cell Tolerance Induction Bud Elongation Involved In Lung Branching C-X-C Chemokine Receptor CXCR4 Signaling Pathway Sodium Channel Inhibitor Activity Ubiquitin-protein Transferase Activity Paraxial Mesoderm Development Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway Regulation Of T Cell Anergy Tube Morphogenesis Protein Polyubiquitination Regulation Of Cellular Response To Growth Factor Stimulus
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