RAP1GAP2

Description		RAP1 GTPase activating protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Adaptive Immune Response Regulation Of Cell Size Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rap1 signalling
Drugs
Diseases
GWAS		Asthma (sex interaction) ( 24824216) Basophil count ( 32888494) Eosinophil count ( 32888494) Femur bone mineral density x serum urate levels interaction ( 34046847) Inflammatory skin disease ( 25574825) Lymphocyte count ( 27863252 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Pre-treatment viral load in HIV-1 infection ( 31219150) Prepulse inhibition of the startle response ( 31596458) Serum metabolite levels ( 33031748) Tonsillectomy ( 27182965 28928442) White blood cell count ( 32888494)
Novel Interacting Genes		1 novel interacting genes: SMG6
Interacting Genes		4 interacting genes: MEOX2 VPS26C YWHAE YWHAZ
Entrez ID		23108
HPRD ID		17028
Ensembl ID		ENSG00000132359
Uniprot IDs		A0A1B0GV05 A0A8V8TKZ8 A0A8V8TL16 Q684P5
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Protein Sequestering Activity Protein Phosphatase Binding Melanosome Establishment Of Localization In Cell Transmembrane Transporter Binding Regulation Of Heart Rate By Hormone Vesicle-mediated Transport To The Plasma Membrane Synaptic Target Recognition Somite Specification Regulation Of Heart Rate By Chemical Signal Protein Targeting Negative Regulation Of Calcium Ion Export Across Plasma Membrane Golgi Reassembly Protein Domain Specific Binding Regulation Of Calcium Ion Export Across Plasma Membrane MAPK Cascade Positive Regulation Of Toll-like Receptor Signaling Pathway
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