FOXL1

Description		forkhead box L1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity DNA Binding, Bending Sequence-specific DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Visceral Mesoderm-endoderm Interaction Involved In Midgut Development Heart Development Anatomical Structure Morphogenesis Regulation Of Wnt Signaling Pathway Cell Differentiation Proteoglycan Biosynthetic Process Peyer's Patch Morphogenesis
Pathways
Drugs
Diseases
GWAS		Bone mineral density ( 24249740) Bone mineral density (hip) ( 19801982) Bone mineral density (spine) ( 19801982) Bone properties (heel) ( 24430505) Colorectal cancer ( 25990418) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 33020668) Dentures ( 31235808) Diverticular disease ( 30177863) Femoral neck bone mineral density ( 22504420 29499414) Haemorrhoidal disease ( 33888516) Incident myocardial infarction ( 26950853) Lateral ventricular volume in normal aging ( 30258056) Lumbar spine bone mineral density ( 29499414) Mild to moderate chronic kidney disease ( 31178898) Multiple system atrophy ( 27629089) Nonsyndromic cleft palate ( 31609978) Nose size ( 27182965) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Obesity-related traits ( 23251661) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Sepsis in extremely premature infants ( 28283553) Systemic juvenile idiopathic arthritis ( 27927641) Urinary albumin-to-creatinine ratio ( 32600054) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes		4 interacting genes: BMPR2 NFIA NFIB NFIC
Entrez ID		2300
HPRD ID		07219
Ensembl ID		ENSG00000176678
Uniprot IDs		Q12952 Q498Y4
PDB IDs
Enriched GO Terms of Interacting Partners?		Retina Development In Camera-type Eye Glial Cell Fate Specification DNA Replication Exit From Mitosis Generation Of Neurons Neuron Fate Specification Glial Cell Proliferation Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Macromolecule Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process BMP Signaling Pathway Cell Fate Specification Positive Regulation Of Nucleobase-containing Compound Metabolic Process Neural Precursor Cell Proliferation Lung Development DNA-binding Transcription Factor Activity Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Lung Ciliated Cell Differentiation Neurogenesis Cell Population Proliferation DNA Metabolic Process Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Mitotic Cell Cycle Phase Transition Cell Differentiation Involved In Salivary Gland Development Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Positive Regulation Of Macromolecule Biosynthetic Process Fibrillar Center Cell Cycle Phase Transition Positive Regulation Of Biosynthetic Process Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Activin Receptor Activity, Type II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Principal Sensory Nucleus Of Trigeminal Nerve Development Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Lung Blood Pressure Cell Junction Pulmonary Valve Development Tricuspid Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Chromatin Response To Wounding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Club Cell Differentiation Positive Regulation Of Macromolecule Metabolic Process
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