SORCS3

Gene Name		sortilin-related VPS10 domain containing receptor 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Integral Component Of Membrane Neuronal Postsynaptic Density
	Molecular Function	Neuropeptide Receptor Activity
	Biological Process	Neuropeptide Signaling Pathway Learning Memory Regulation Of Long Term Synaptic Depression
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: NGF
Entrez ID		22986
HPRD ID		12100
Ensembl ID		ENSG00000156395
Uniprot IDs		Q9UPU3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Neuron Maturation Nerve Growth Factor Processing Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Regulation Of Neuron Maturation Response To Ozone Regulation Of Neurotrophin TRK Receptor Signaling Pathway Nerve Growth Factor Signaling Pathway Positive Regulation Of Protein Autophosphorylation Cellular Response To Nerve Growth Factor Stimulus Regulation Of Protein Autophosphorylation Peptide Hormone Processing Response To Nicotine Positive Regulation Of Axon Extension Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Response To Electrical Stimulus Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Neuron Apoptotic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Neuron Death Activation Of MAPKK Activity Regulation Of Neurotransmitter Secretion Regulation Of Axon Extension Positive Regulation Of Stem Cell Proliferation Positive Regulation Of Axonogenesis Positive Regulation Of Phospholipase Activity Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Sensory Perception Of Pain Extrinsic Apoptotic Signaling Pathway Peripheral Nervous System Development Regulation Of Stem Cell Proliferation Adult Locomotory Behavior Positive Regulation Of Cell Growth Memory Regulation Of Cell Size Phosphatidylinositol-mediated Signaling Response To Alkaloid Peptide Metabolic Process Positive Regulation Of Developmental Growth Response To Glucocorticoid Regulation Of Axonogenesis Regulation Of Ion Homeostasis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Adult Behavior Response To Corticosteroid Circadian Rhythm
Tagcloud ?		anterograde autosomal bdnf cargo cargos coat endosomes frontotemporal golgi intercellular lobar modulate neurodegeneration neurotrophic pleiotropic proneurotrophins retromer sorl1 sortilin sorting summarizes synapse trafficking trk vacuolar vital vps10