PLA2R1

Gene Name		phospholipase A2 receptor 1, 180kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Carbohydrate Binding Phospholipase Binding
	Biological Process	Cytokine Production Endocytosis Receptor-mediated Endocytosis Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Reactive Oxygen Species Metabolic Process Positive Regulation Of Arachidonic Acid Secretion Replicative Senescence Oxidative Stress-induced Premature Senescence Negative Regulation Of Phospholipase A2 Activity Negative Regulation Of Arachidonic Acid Secretion
Pathways
Drugs
Diseases
GWAS		Bilirubin levels ( 20639394) Nephropathy (idiopathic membranous) ( 21323541)
Protein-protein Interactions		2 interactors: PLA2G10 PLA2G2A
Entrez ID		22925
HPRD ID		09222
Ensembl ID		ENSG00000153246
Uniprot IDs		B7ZML4 Q13018
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol Acyl-chain Remodeling Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Phosphatidylserine Metabolic Process Positive Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Macrophage Derived Foam Cell Differentiation Phosphatidylcholine Metabolic Process Cellular Biogenic Amine Metabolic Process Amine Metabolic Process Glycerophospholipid Biosynthetic Process Lysophospholipid Transport Phosphatidylinositol Metabolic Process Phospholipid Biosynthetic Process Lipid Catabolic Process Cellular Modified Amino Acid Metabolic Process Glycerophospholipid Metabolic Process Alcohol Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Negative Regulation Of Cholesterol Efflux Positive Regulation Of Arachidonic Acid Secretion Lipid Biosynthetic Process Regulation Of Arachidonic Acid Secretion Negative Regulation Of Cholesterol Transport Low-density Lipoprotein Particle Remodeling Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Cell Differentiation Positive Regulation Of Icosanoid Secretion Cellular Lipid Metabolic Process Organophosphate Metabolic Process Regulation Of Cholesterol Efflux Negative Regulation Of Lipid Transport Positive Regulation Of Fatty Acid Transport Regulation Of Macrophage Activation Plasma Lipoprotein Particle Remodeling Regulation Of Fatty Acid Transport Positive Regulation Of Lipid Storage Lipid Metabolic Process Regulation Of Cholesterol Transport Carbohydrate Derivative Transport Regulation Of Cell Differentiation Regulation Of Lipid Storage Positive Regulation Of Lipid Transport Regulation Of Plasma Lipoprotein Particle Levels Arachidonic Acid Metabolic Process Defense Response To Gram-positive Bacterium
Tagcloud ?		2000s alloimmune ancestry basel cationic come definition deposited dqa1 endopeptidase exaggerated faithful heymann idiopathic inspired karger membranous mn nephritis nephropathy opening pathomechanisms personalized phospholipase revisit signatures uncertainties uniform