IKZF2

Gene Name		IKAROS family zinc finger 2 (Helios)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Molecular_function DNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Biological_process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 19198610)
Protein-protein Interactions		9 interactors: AQP1 CTBP1 CTBP2 HDAC4 HOXA1 IKZF1 IKZF4 IKZF5 LONRF1
Entrez ID		22807
HPRD ID		05872
Ensembl ID		ENSG00000030419
Uniprot IDs		B4DWF2 Q9UKS7
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter White Fat Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Biosynthetic Process RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Viral Genome Replication Gene Expression Cellular Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Response To Retinoic Acid Regulation Of Gene Expression Positive Regulation Of Neutrophil Differentiation Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process B Cell Differentiation Facial Nucleus Development Carbon Dioxide Transmembrane Transport Corticotropin Secretion Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Tagcloud ?		aggressive aiolos alterations aneuploidy chromosomes commonly differ encoding exome explored haploid harbor helios hypodiploid ikzf3 leukemic lymphoblastic lymphoid near nontumor phosphoinositide pi3k profiles profiling ras rb1 submicroscopic subtype tp53