FGL1

Description		fibrinogen like 1
Image
GO Annotations	Cellular Component	Extracellular Region Fibrinogen Complex Extracellular Space Extracellular Matrix
	Molecular Function	Protein Binding
	Biological Process	Adaptive Immune Response Immune System Process Blood Coagulation Regulation Of Immune Response Negative Regulation Of T Cell Activation Hepatocyte Proliferation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		3 interacting genes: BCL2L11 GLP1R VKORC1
Entrez ID		2267
HPRD ID		09312
Ensembl ID		ENSG00000104760
Uniprot IDs		Q08830
PDB IDs		7TZ2
Enriched GO Terms of Interacting Partners?		Glucagon-like Peptide 1 Receptor Activity BIM-BCL-2 Complex BIM-BCL-xl Complex Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Glucagon Receptor Activity Apoptotic Process Involved In Embryonic Digit Morphogenesis Response To Psychosocial Stress Post-translational Protein Targeting To Membrane, Translocation Cellular Response To Glucagon Stimulus Activation Of Adenylate Cyclase Activity Cellular Response To Hormone Stimulus Positive Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Ear Development Regulation Of Developmental Pigmentation Positive Regulation Of T Cell Apoptotic Process Bcl-2 Family Protein Complex Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of IRE1-mediated Unfolded Protein Response Thymocyte Apoptotic Process Developmental Pigmentation Quinone Binding Peptidyl-glutamic Acid Modification Vitamin K Metabolic Process Positive Regulation Of Lyase Activity Regulation Of Biological Quality Positive Regulation Of Adenylate Cyclase Activity Response To Glucagon Regulation Of Fibroblast Apoptotic Process Regulation Of IRE1-mediated Unfolded Protein Response Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Positive Regulation Of Lymphocyte Apoptotic Process Positive Regulation Of Cyclase Activity Response To Hormone Apoptotic Process Involved In Morphogenesis Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Intracellular Protein Transmembrane Transport Regulation Of Multicellular Organismal Process Positive Regulation Of Blood Pressure B Cell Homeostasis T Cell Apoptotic Process Positive Regulation Of Membrane Permeability Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Leukocyte Apoptotic Process Myeloid Cell Homeostasis
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