GPC5

Description		glypican 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Golgi Lumen Plasma Membrane Cell Surface Membrane Lysosomal Lumen Side Of Membrane
	Molecular Function	Protein Binding
	Biological Process	Regulation Of Signal Transduction Cell Migration Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Localization To Membrane
Pathways		Glycosaminoglycan-protein linkage region biosynthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Release of Hh-Np from the secreting cell Attachment and Entry Attachment and Entry Retinoid metabolism and transport Respiratory syncytial virus (RSV) attachment and entry RSV-host interactions
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065) Blood pressure (smoking interaction) ( 25189868) Blood protein levels ( 30072576) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 25429064 25282103 20189936 20881960) HIV-1 viral setpoint ( 20205591) Incident coronary heart disease ( 26950853) Interleukin-6 levels ( 33517400) Lung cancer ( 20304703) Metabolite levels ( 19043545 23823483) Multiple sclerosis ( 19010793) Nephrotic syndrome (acquired) ( 21441931) Neurological blood protein biomarker levels ( 31320639) Obesity-related traits ( 23251661) Rapid automised naming of letters ( 30741946) Refractive astigmatism ( 30306274) Rheumatoid arthritis ( 30423114) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Tetralogy of Fallot ( 23297363) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		1 interacting genes: DCPS
Entrez ID		2262
HPRD ID		03902
Ensembl ID		ENSG00000179399
Uniprot IDs		P78333
PDB IDs
Enriched GO Terms of Interacting Partners?		5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA 7-methylguanosine Cap Binding Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Methylguanosine-cap Decapping RNA Exonuclease Activity MRNA Cis Splicing, Via Spliceosome RNA Decapping RNA Destabilization Positive Regulation Of MRNA Catabolic Process MRNA Destabilization P-body Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability RNA Catabolic Process RNA Splicing, Via Transesterification Reactions
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