FECH

Gene Name		ferrochelatase
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Ferrochelatase Activity Protein Binding Ferrous Iron Binding Heme Binding Iron-responsive Element Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Porphyrin-containing Compound Metabolic Process Heme Biosynthetic Process Cholesterol Metabolic Process Response To Light Stimulus Detection Of UV Response To Lead Ion Regulation Of Gene Expression Regulation Of EIF2 Alpha Phosphorylation By Heme Response To Insecticide Erythrocyte Differentiation Very-low-density Lipoprotein Particle Assembly Response To Drug Small Molecule Metabolic Process Response To Ethanol Protoporphyrinogen IX Metabolic Process Response To Arsenic-containing Substance Regulation Of Hemoglobin Biosynthetic Process Response To Methylmercury Iron Ion Homeostasis Response To Platinum Ion Cellular Response To Dexamethasone Stimulus
Pathways		Heme biosynthesis Metabolism of porphyrins
Drugs		Cholic Acid
Diseases
GWAS
Protein-protein Interactions		1 interactors: ABCB7
Entrez ID		2235
HPRD ID		01509
Ensembl ID
Uniprot IDs		B4DSA4 P22830 Q7KZA3
PDB IDs		1HRK 2HRC 2HRE 2PNJ 2PO5 2PO7 2QD1 2QD2 2QD3 2QD4 2QD5 3AQI 3HCN 3HCO 3HCP 3HCR 4F4D 4MK4
Enriched GO Terms of Interacting Partners?		Heme Transport Cofactor Transport Cellular Iron Ion Homeostasis Iron Ion Homeostasis Transition Metal Ion Homeostasis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Ion Homeostasis
Tagcloud ?		abcb6 ambp antioxidant beyond candidates chosen erythroid erythropoiesis followup fth1 ftl globin heme heterodimerizes hrg isothiocyanate k562 keap1 lymphoid maf nfe2 nfe2l2 nqo1 nrf2 seq sfn slc48a1 sulforaphane tbxas1