FDXR

Description		ferredoxin reductase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane
	Molecular Function	Ferredoxin-NADP+ Reductase Activity Oxidoreductase Activity
	Biological Process	Generation Of Precursor Metabolites And Energy Lipid Metabolic Process Steroid Biosynthetic Process Ubiquinone Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process
Pathways		Pregnenolone biosynthesis Endogenous sterols Electron transport from NADPH to Ferredoxin Defective CYP11A1 causes AICSR
Drugs		Flavin adenine dinucleotide Nicotinamide adenine dinucleotide phosphate
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		5 interacting genes: FDX1 FHIT MTNR1A OGT POU2F1
Entrez ID		2232
HPRD ID		00060
Ensembl ID		ENSG00000161513
Uniprot IDs		A0A0A0MSZ4 A0A0A0MT64 A0A0A0MTN9 A0A0A0MTR6 A0A0C4DFN8 A0A0C4DGN7 P22570
PDB IDs
Enriched GO Terms of Interacting Partners?		Adenylylsulfatase Activity Adenylylsulfate-ammonia Adenylyltransferase Activity Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Diadenosine Triphosphate Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly P450-containing Electron Transport Chain Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Circadian Rhythm Negative Regulation Of Proteolysis Bis(5'-adenosyl)-triphosphatase Activity Protein O-acetylglucosaminyltransferase Activity Diadenosine Polyphosphate Catabolic Process Adenosine 5'-monophosphoramidase Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Melatonin Receptor Activity Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Carbon Catabolite Regulation Of Transcription Rhythmic Process Regulation Of Transcription By Glucose NSL Complex Cellular Response To Forskolin Regulation Of Proteolysis Negative Regulation Of Catabolic Process Regulation Of Protein Catabolic Process Hormone Binding Response To Forskolin Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
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