SP8

Gene Name		Sp8 transcription factor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	DNA Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Dorsal/ventral Pattern Formation Proximal/distal Pattern Formation Embryonic Limb Morphogenesis
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 20386566) Prostate cancer ( 23535732) Response to statin therapy ( 20339536)
Protein-protein Interactions		3 interactors: HEYL ZNF273 ZNF519
Entrez ID		221833
HPRD ID		12208
Ensembl ID
Uniprot IDs		Q8IXZ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Androgen Receptor Activity Proximal Tubule Development Transcription, DNA-templated RNA Biosynthetic Process Pulmonary Valve Morphogenesis Negative Regulation Of Androgen Receptor Signaling Pathway Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Endocardial Cushion Formation RNA Metabolic Process Regulation Of Androgen Receptor Signaling Pathway Atrioventricular Valve Morphogenesis Endocardial Cushion Morphogenesis Atrioventricular Valve Development Gene Expression Negative Regulation Of Receptor Activity Cellular Response To BMP Stimulus Cardiac Epithelial To Mesenchymal Transition Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Ventricular Septum Morphogenesis Heart Valve Morphogenesis Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Heart Valve Development Endocardial Cushion Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Ventricular Septum Development Epithelial To Mesenchymal Transition Cardiac Septum Morphogenesis Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Skeletal Muscle Cell Differentiation Outflow Tract Morphogenesis Glomerulus Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Cardiac Ventricle Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cardiac Septum Development Renal Tubule Development Nitrogen Compound Metabolic Process Cardiac Ventricle Development Mesenchymal Cell Development Regulation Of Receptor Activity Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
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