FGD2

Description		FYVE, RhoGEF and PH domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Endosome Early Endosome Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Early Endosome Membrane Ruffle Membrane Cell Projection
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Regulation Of GTPase Activity Filopodium Assembly Regulation Of Small GTPase Mediated Signal Transduction
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events CDC42 GTPase cycle
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Medication use (thyroid preparations) ( 31015401) Monocyte count ( 32888494) Rosacea symptom severity ( 29771307)
Interacting Genes		5 interacting genes: CDC42 KLHL12 PLEKHG4 RPRM TMEM239
Entrez ID		221472
HPRD ID		05478
Ensembl ID		ENSG00000146192
Uniprot IDs		Q7Z6J4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?