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FGD2
Gene Name
FYVE, RhoGEF and PH domain containing 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Nucleus
Cytoplasm
Golgi Apparatus
Cytosol
Cytoskeleton
Lamellipodium
Early Endosome Membrane
Ruffle Membrane
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Small GTPase Binding
Metal Ion Binding
Biological Process
Cytoskeleton Organization
Small GTPase Mediated Signal Transduction
Regulation Of Cell Shape
Actin Cytoskeleton Organization
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Apoptotic Process
Regulation Of Cdc42 GTPase Activity
Positive Regulation Of GTPase Activity
Filopodium Assembly
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Apoptotic Signaling Pathway
Pathways
Rho GTPase cycle
Signaling by GPCR
GPCR downstream signaling
Signalling by NGF
Cell death signalling via NRAGE, NRIF and NADE
Signaling by Rho GTPases
NRAGE signals death through JNK
G alpha (12/13) signalling events
p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Protein-protein Interactions
2 interactors:
KLHL12
TMEM239
Entrez ID
221472
HPRD ID
05478
Ensembl ID
ENSG00000146192
Uniprot IDs
Q7Z6J4
PDB IDs
Enriched GO Terms of Interacting Partners
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COPII Vesicle Coating
COPII-coated Vesicle Budding
Vesicle Targeting, To, From Or Within Golgi
Protein Monoubiquitination
Localization Within Membrane
Vesicle Targeting
Membrane Budding
ER To Golgi Vesicle-mediated Transport
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Wnt Signaling Pathway
Establishment Of Vesicle Localization
Vesicle Organization
Vesicle Localization
Regulation Of Canonical Wnt Signaling Pathway
Golgi Vesicle Transport
Wnt Signaling Pathway
Regulation Of Wnt Signaling Pathway
Establishment Of Organelle Localization
Tagcloud
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