ALDH3B1

Description		aldehyde dehydrogenase 3 family member B1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Secretory Granule Membrane Vesicle Specific Granule Membrane Extracellular Exosome
	Molecular Function	3-chloroallyl Aldehyde Dehydrogenase Activity Aldehyde Dehydrogenase (NAD+) Activity Aldehyde Dehydrogenase [NAD(P)+] Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor Benzaldehyde Dehydrogenase (NADP+) Activity Benzaldehyde Dehydrogenase (NAD+) Activity Aldehyde Dehydrogenase (NADP+) Activity Long-chain Fatty Aldehyde Dehydrogenase (NAD+) Activity Medium-chain Fatty Aldehyde Dehydrogenase (NAD+) Activity
	Biological Process	Alcohol Metabolic Process Ethanol Catabolic Process Aldehyde Metabolic Process Lipid Metabolic Process Response To Oxidative Stress Sphingolipid Catabolic Process Cellular Response To Oxidative Stress Aldehyde Catabolic Process
Pathways		Neutrophil degranulation Sphingolipid catabolism
Drugs		NADH
Diseases
GWAS		Serum uric acid levels ( 32514006)
Interacting Genes		18 interacting genes: CYSRT1 HSD17B10 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP3-3 KRTAP4-2 KRTAP5-9 MID2 NOTCH2NLA
Entrez ID		221
HPRD ID		02716
Ensembl ID		ENSG00000006534
Uniprot IDs		A0A087X2D4 P43353
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Epidermis Development Structural Molecule Activity Cytosol Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Identical Protein Binding Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity Cholate 7-alpha-dehydrogenase (NAD+) Activity Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity Brexanolone Metabolic Process Mitochondrial Ribonuclease P Complex Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing Mitochondrial TRNA Methylation Mitochondrial RNA 5'-end Processing
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