FAP

Gene Name		fibroblast activation protein, alpha
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Focal Adhesion Cell Surface Integral Component Of Membrane Lamellipodium Lamellipodium Membrane Ruffle Membrane Apical Part Of Cell Basal Part Of Cell Invadopodium Membrane
	Molecular Function	Protease Binding Endopeptidase Activity Metalloendopeptidase Activity Serine-type Endopeptidase Activity Integrin Binding Protein Binding Peptidase Activity Serine-type Peptidase Activity Dipeptidyl-peptidase Activity Protein Homodimerization Activity Protein Dimerization Activity
	Biological Process	Angiogenesis Proteolysis Cell Adhesion Regulation Of Collagen Catabolic Process Negative Regulation Of Extracellular Matrix Disassembly Endothelial Cell Migration Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Fibrinolysis Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Positive Regulation Of Cell Cycle Arrest Mitotic Cell Cycle Arrest Melanocyte Proliferation Positive Regulation Of Execution Phase Of Apoptosis Melanocyte Apoptotic Process Negative Regulation Of Extracellular Matrix Organization
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: DPP4 PLAUR
Entrez ID		2191
HPRD ID		02674
Ensembl ID		ENSG00000078098
Uniprot IDs		B4DLR2 Q12884
PDB IDs		1Z68
Enriched GO Terms of Interacting Partners?		Urokinase Plasminogen Activator Signaling Pathway Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Extracellular Matrix Organization Regulation Of Cell-cell Adhesion Mediated By Integrin Attachment Of GPI Anchor To Protein C-terminal Protein Lipidation Fibrinolysis Regulation Of Extracellular Matrix Disassembly Locomotion Regulation Of Extracellular Matrix Organization Regulation Of Cell Adhesion Mediated By Integrin Movement Of Cell Or Subcellular Component Negative Regulation Of Blood Coagulation GPI Anchor Biosynthetic Process Negative Regulation Of Coagulation GPI Anchor Metabolic Process Negative Regulation Of Wound Healing T Cell Costimulation Endothelial Cell Migration Glycolipid Biosynthetic Process Regulation Of Blood Coagulation Epithelial Cell Migration Epithelium Migration Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Regulation Of Wound Healing Glycolipid Metabolic Process
Tagcloud ?		adenomatous carriers decline distress emotions experience familial formerly hboc hd hereditary huntington inclined learned marginally noncarriers paradigm polyposis predictive psychological qualitative sharp steady tended testing trend unchanged undertaken ward