EZH1

Gene Name		enhancer of zeste 1 polycomb repressive complex 2 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm ESC/E(Z) Complex
	Molecular Function	Chromatin Binding Histone Methyltransferase Activity (H3-K27 Specific)
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Anatomical Structure Morphogenesis Histone H3-K27 Methylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: E2F6 EED ZMYND11
Entrez ID		2145
HPRD ID		03397
Ensembl ID		ENSG00000108799
Uniprot IDs		Q92800
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Histone H3-K27 Methylation Regulation Of Histone H3-K27 Methylation Chromatin Modification RNA Metabolic Process Chromatin Organization Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression By Genetic Imprinting Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of JNK Cascade Genetic Imprinting Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Histone Methylation Chromosome Organization Regulation Of Transcription, DNA-templated Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription, Elongation Regulation Of Histone Methylation Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Histone Modification Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Cell Cycle Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Histone Methylation Regulation Of Histone Modification Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of MAPK Cascade G1/S Transition Of Mitotic Cell Cycle Regulation Of JNK Cascade
Tagcloud ?		coimmunoprecipitation combs continuously delimited demonstrates directed discuss disrupt drosophila earlier embryo embryogenesis enhancer esc evolution extra heed homologs hybrid impair maintain partnership pc polycomb repressors silencing zeste