ETV4

Name	ETS variant transcription factor 4
Structure
Interactors	15 interactors: APP ATXN1 EP300 EPAS1 HIF1A HOXD4 HTT JUN MEOX2 NFE2L2 SAE1 SMAD4 SRF STK11 UBA2
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Nucleolus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways	MAPK6/MAPK4 signaling
Diseases	Prostate cancer Ewing's sarcoma
GWAS	No GWAS studies recorded
Entrez ID	2118
HPRD ID	02833
Ensembl ID	ENSG00000175832
Uniprot IDs	P43268
PDB IDs	4CO8 4UUV 5ILU
GO Terms Enriched among Interactors ?	Positive Regulation Of Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of MiRNA Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Learning Or Memory DNA Binding Transcription Coactivator Binding Response To Hypoxia Regulation Of Metabolic Process Positive Regulation Of MiRNA Transcription Response To Decreased Oxygen Levels Cognition Learning Response To Oxygen Levels Positive Regulation Of MiRNA Metabolic Process Regulation Of Primary Metabolic Process Hemopoiesis Nucleoplasm Nucleus P53 Binding Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process SUMO Activating Enzyme Activity SUMO Activating Enzyme Complex Positive Regulation Of Biosynthetic Process Regulation Of Protein Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Metabolic Process Associative Learning Transcription Regulator Complex Sequence-specific DNA Binding Negative Regulation Of MiRNA Transcription Chromatin Binding Positive Regulation Of Multicellular Organismal Process Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of Transport Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transcription By RNA Polymerase II Positive Regulation Of Cell Differentiation Nervous System Process