SLC44A5

Description		solute carrier family 44 member 5
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Protein Binding Choline Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity
	Biological Process	Phosphatidylcholine Biosynthetic Process Choline Transport Transmembrane Transport
Pathways		Synthesis of PC SLC-mediated bile acid transport
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933) Self-reported tiredness ( 28194004) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352) Whole-brain volume (Alzheimer's disease interaction) ( 21116278)
Novel Interacting Genes		1 novel interacting genes: NEGR1
Interacting Genes		1 interacting genes: CFTR
Entrez ID		204962
HPRD ID		14580
Ensembl ID		ENSG00000137968
Uniprot IDs		B7Z5Y4 Q8NCS7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Secretion Positive Regulation Of Anion Channel Activity Regulation Of Body Fluid Levels Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Saliva Secretion Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Regulation Of Saliva Secretion Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Negative Regulation Of Synapse Assembly Regulation Of Secretion Positive Regulation Of Digestive System Process Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Negative Regulation Of Synapse Organization Apical Dendrite Lipid Droplet Formation Response To Forskolin Negative Regulation Of Glial Cell Proliferation Chloride Transmembrane Transporter Activity Sperm Capacitation Positive Regulation Of Transport Skeletal Muscle Organ Development Chemical Homeostasis Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Vesicle Docking Involved In Exocytosis Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Positive Regulation Of Transporter Activity Sterol Biosynthetic Process ABC-type Transporter Activity Transepithelial Transport
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