EMX2

Name	empty spiracles homeobox 2
Structure	No pdb structure
Interactors	5 interactors: EIF4E GTF2A1L MEIS1 OTUD6A TLE2
GO Annotations	Cellular Component	Chromatin Nucleus Axon Cell Projection
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Neuron Migration Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Response To Xenobiotic Stimulus Anterior/posterior Pattern Specification Regulation Of Gene Expression Dentate Gyrus Development Cerebral Cortex Regionalization Cell Proliferation In Forebrain Forebrain Cell Migration Cerebral Cortex Development Neuron Differentiation Forebrain Development Ureter Morphogenesis Stereocilium Bundle Organization
Pathways	Formation of the nephric duct
GWAS	Airflow obstruction ( 22837378 ) Celiac disease ( 23936387 ) Chronotype ( 30696823 ) Double-edged eyelids ( 29895819 ) Early cardiac repolarization ( 22683750 ) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828 ) Liver fibrosis (total hepatic collagen content) ( 32953199 ) Low tan response ( 29739929 ) Neuroticism ( 29255261 ) Obesity-related traits ( 23251661 ) Ovarian disease with few adhesions ( 28333195 ) Photic sneeze reflex ( 27182965 ) Pulmonary function in asthmatics ( 23541324 ) Response to quetiapine in schizophrenia ( 29503163 ) Serum uric acid levels ( 29403010 30993211 ) Skin pigmentation ( 30664655 ) Skin, hair and eye pigmentation (multivariate analysis) ( 30664655 ) Urate levels ( 31578528 )
Entrez ID	2018
HPRD ID	02495
Ensembl ID	ENSG00000170370
Uniprot IDs	Q04743
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Eukaryotic Initiation Factor 4G Binding MRNA Cap Binding Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Regulation Of Neuron Differentiation Regulation Of Translation At Postsynapse Negative Regulation Of Neuron Differentiation Transcription Factor TFIIA Complex Protein K33-linked Deubiquitination Protein K27-linked Deubiquitination Protein K29-linked Deubiquitination Transcription Regulator Complex Cell Growth Involved In Cardiac Muscle Cell Development