FBXO45

Gene Name		F-box protein 45
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Postsynaptic Density Cell Junction Presynaptic Membrane Postsynaptic Membrane
	Molecular Function	Protein Binding
	Biological Process	Neuron Migration Cellular Response To DNA Damage Stimulus Protein Ubiquitination Cerebral Cortex Radially Oriented Cell Migration Cerebral Cortex Tangential Migration Corticospinal Tract Morphogenesis Anterior Commissure Morphogenesis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Synapse Assembly Involved In Innervation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: PAWR TP73
Entrez ID		200933
HPRD ID		19508
Ensembl ID		ENSG00000174013
Uniprot IDs		P0C2W1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Interleukin-2 Biosynthetic Process Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cerebrospinal Fluid Secretion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Interleukin-2 Production Positive Regulation Of Cell Death Negative Regulation Of Cell Proliferation Negative Regulation Of JUN Kinase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Glycoprotein Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Cell Size Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of B Cell Proliferation Negative Regulation Of T Cell Receptor Signaling Pathway Apoptotic Process Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Cardiac Muscle Tissue Development Programmed Cell Death Cytokine Biosynthetic Process Cell Death Death Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Regulation Of Glycoprotein Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cytokine Metabolic Process Negative Regulation Of Signaling Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Negative Regulation Of JNK Cascade Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Metabolic Process Negative Regulation Of Stress-activated MAPK Cascade Negative Regulation Of B Cell Activation Negative Regulation Of Gene Expression Negative Regulation Of Organ Growth Positive Regulation Of Glial Cell Differentiation Negative Regulation Of Biosynthetic Process
Tagcloud ?		asd asds autism connectivity contributors deleterious hamartin idiopathic intronic mounting mtorc1 mycbp2 neurodevelopment pam pools proband representation resequenced rheb sanger simons splice synapse trios tsc tsc1 tsc2 tuberin variants