EIF2S3

Gene Name		eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Translation Initiation Factor Activity GTPase Activity Protein Binding GTP Binding Translation Factor Activity, Nucleic Acid Binding
	Biological Process	Translation Translational Initiation Gene Expression Cellular Protein Metabolic Process
Pathways		Ribosomal scanning and start codon recognition Recycling of eIF2:GDP Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: METAP2 NDRG1
Entrez ID		1968
HPRD ID		02155
Ensembl ID
Uniprot IDs		P41091
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Initiator Methionine Removal Positive Regulation Of Spindle Checkpoint Peptidyl-methionine Modification Positive Regulation Of Cell Cycle Checkpoint Peripheral Nervous System Myelin Maintenance Regulation Of Spindle Checkpoint Regulation Of Rhodopsin Mediated Signaling Pathway Response To Abiotic Stimulus N-terminal Protein Amino Acid Modification Myelin Maintenance Rhodopsin Mediated Signaling Pathway Mast Cell Activation Regulation Of Cell Cycle Checkpoint Myelination In Peripheral Nervous System Schwann Cell Development Schwann Cell Differentiation Phototransduction, Visible Light DNA Damage Response, Signal Transduction By P53 Class Mediator Detection Of Visible Light Signal Transduction In Response To DNA Damage Cellular Response To Light Stimulus Phototransduction Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Glial Cell Development Peripheral Nervous System Development Detection Of Light Stimulus Cellular Response To Oxygen Levels Signal Transduction By P53 Class Mediator Cellular Response To Radiation Myelination Axon Ensheathment Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Glial Cell Differentiation Plasma Membrane Organization Positive Regulation Of Cell Cycle Process Gliogenesis Protein Processing
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