METTL15

Description		methyltransferase 15, mitochondrial 12S rRNA N4-cytidine
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity RRNA (cytosine-N4-)-methyltransferase Activity
	Biological Process	Methylation RRNA Base Methylation
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Body size at age 10 ( 32376654) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Childhood body mass index ( 33045005) Chronotype ( 30696823) Daytime nap ( 33568662) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Hip circumference adjusted for BMI ( 28552196) Intraocular pressure ( 31959993) Major depressive disorder (MTAG) ( 33479212) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 27841878) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Type 2 diabetes (adjusted for BMI) ( 30297969)
Interacting Genes		14 interacting genes: CIDEC CSTF2 FANCL GLYCTK HOXC8 MAPKBP1 MSRB3 NEK6 PEF1 PROP1 SPAG8 TRIP13 USHBP1 VAC14
Entrez ID		196074
HPRD ID		08750
Ensembl ID		ENSG00000169519
Uniprot IDs		A6NJ78
PDB IDs		7PNX 7PNY 7PNZ 8IPI 8IPK 8IPL 8IPM 8QRL
Enriched GO Terms of Interacting Partners?
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