DUSP7

Gene Name		dual specificity phosphatase 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Inactivation Of MAPK Activity Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Peptidyl-tyrosine Dephosphorylation TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Negative Regulation Of MAP Kinase Activity Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Stress-activated MAPK Cascade
Pathways		Toll Like Receptor 7/8 (TLR7/8) Cascade ERKs are inactivated Toll Like Receptor TLR6:TLR2 Cascade Activated TLR4 signalling Toll Like Receptor TLR1:TLR2 Cascade MyD88 cascade initiated on plasma membrane Toll Like Receptor 5 (TLR5) Cascade MyD88 dependent cascade initiated on endosome TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88:Mal cascade initiated on plasma membrane Toll Like Receptor 9 (TLR9) Cascade ERK/MAPK targets Innate Immune System ERKs are inactivated Signalling by NGF MAP kinase activation in TLR cascade TRIF-mediated TLR3/TLR4 signaling NGF signalling via TRKA from the plasma membrane MyD88-independent cascade Toll Like Receptor 2 (TLR2) Cascade Toll-Like Receptors Cascades Toll Like Receptor 10 (TLR10) Cascade Toll Like Receptor 3 (TLR3) Cascade Toll Like Receptor 4 (TLR4) Cascade ERK/MAPK targets MAPK targets/ Nuclear events mediated by MAP kinases Nuclear Events (kinase and transcription factor activation)
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: EEF1A1 GHR MAPK1 MAPK14 MAPK8
Entrez ID		1849
HPRD ID		04125
Ensembl ID		ENSG00000164086
Uniprot IDs		Q16829
PDB IDs
Enriched GO Terms of Interacting Partners?		Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Peptidyl-serine Phosphorylation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Response To Growth Factor Stimulus Activation Of MAPK Activity Response To Growth Factor Activation Of Innate Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Response To Lipid MAPK Cascade Neurotrophin Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Growth Hormone Receptor Signaling Pathway Regulation Of Innate Immune Response Cellular Response To Growth Hormone Stimulus Peptidyl-amino Acid Modification Response To Epidermal Growth Factor Response To Organic Substance Activation Of Protein Kinase Activity Signal Transduction By Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Response To Lipopolysaccharide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Lipopolysaccharide-mediated Signaling Pathway Response To Molecule Of Bacterial Origin Response To Growth Hormone Peptidyl-threonine Phosphorylation Positive Regulation Of Signal Transduction
Tagcloud ?		accumulate altering arf ascribe ascribed atm atr brca2 checkpoint dusp4 enables encode inactivate integrity lacking pair phosphatases rad51 recapitulated replicative reversed se senescence stabilizes suppressor surprisingly triggers tumour unanticipated