DSG3

Gene Name		desmoglein 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Membrane Desmosome Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding
	Biological Process	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Pathways		Apoptotic cleavage of cell adhesion proteins Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS		Parkinson's disease (age of onset) ( 19772629)
Protein-protein Interactions		4 interactors: CASP3 FURIN JUP PKP3
Entrez ID		1830
HPRD ID		01355
Ensembl ID		ENSG00000134757
Uniprot IDs		P32926
PDB IDs
Enriched GO Terms of Interacting Partners?		Desmosome Assembly Desmosome Organization Establishment Of Protein Localization To Plasma Membrane Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Extracellular Matrix Disassembly Cell-cell Junction Assembly Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Enzyme Linked Receptor Protein Signaling Pathway Protein Localization To Plasma Membrane Nerve Growth Factor Production Cell Junction Assembly Cell-cell Junction Organization Endothelial Cell-cell Adhesion Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Receptor Catabolic Process Neurotrophin TRK Receptor Signaling Pathway Skin Development Plasma Membrane Organization Neurotrophin Signaling Pathway Establishment Of Protein Localization To Membrane Protein Processing Nerve Growth Factor Processing Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Cellular Response To Indole-3-methanol Positive Regulation Of Proteolysis Negative Regulation Of Transforming Growth Factor Beta Production Glial Cell Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Bundle Of His Cell To Purkinje Myocyte Communication Protein Localization To Membrane Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Viral Protein Processing Cytoskeletal Anchoring At Plasma Membrane Cellular Response To Organic Substance Endomembrane System Organization Negative Regulation Of Activated T Cell Proliferation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Membrane Protein Ectodomain Proteolysis Peptidyl-glutamic Acid Carboxylation Negative Regulation Of B Cell Proliferation Single Organismal Cell-cell Adhesion Signal Peptide Processing Apoptotic DNA Fragmentation Regulation Of Cell Fate Specification Ventricular Cardiac Muscle Cell Action Potential Cellular Response To Growth Factor Stimulus Platelet Formation
Tagcloud ?		cadherins companion continuity desmocollin desmoglein desmoplakin desmosomal desmosomes displaying dsc1 dsc2 dsc3 dsg1 dsg2 exclusive follicle hair immunopositive mutually ontogenic outer plakoglobin plakophilin practically rood root sheath subinfundibular trichocytes