DPYS

Description		dihydropyrimidinase
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Dihydropyrimidinase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Identical Protein Binding Metal Ion Binding Phosphoprotein Binding
	Biological Process	Pyrimidine Nucleobase Catabolic Process Thymine Catabolic Process Uracil Catabolic Process CMP Catabolic Process DCMP Catabolic Process UMP Catabolic Process DUMP Catabolic Process
Pathways		Pyrimidine catabolism
Drugs
Diseases		Dihydropyrimidinase deficiency; Dihydropyrimidinuria
GWAS		Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) Hallux valgus ( 32131869) Irritable mood ( 29500382) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Salivary metabolite levels ( 31960908)
Interacting Genes		2 interacting genes: APPBP2 DPYSL5
Entrez ID		1807
HPRD ID		01960
Ensembl ID		ENSG00000147647
Uniprot IDs		Q14117
PDB IDs		2VR2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Dendrite Morphogenesis Pyrimidine Nucleobase Catabolic Process Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides Dihydropyrimidinase Activity Cul2-RING Ubiquitin Ligase Complex Pyrimidine Nucleobase Metabolic Process Pyrimidine-containing Compound Catabolic Process Microtubule Associated Complex
Tagcloud ?