AGA

Description		aspartylglucosaminidase
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Lysosome Endoplasmic Reticulum Azurophil Granule Lumen
	Molecular Function	N4-(beta-N-acetylglucosaminyl)-L-asparaginase Activity Protein Binding Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Protein Deglycosylation
Pathways		Neutrophil degranulation
Drugs
Diseases		Aspartylglucosaminuria (AGU)
GWAS		Chromosomal aberration frequency (chromatid type) ( 31586183) Colorectal cancer (calcium intake interaction) ( 25192705) Familial hepatitis B virus-related hepatocellular carcinoma ( 28662289) Metabolite levels ( 23823483) Motion sickness ( 25628336) Response to mTOR inhibitor (everolimus) ( 24009623) Serum metabolite levels ( 33031748) Serum selenium levels ( 23698163)
Interacting Genes		3 interacting genes: ALB IGF2R KRTAP1-3
Entrez ID		175
HPRD ID		01949
Ensembl ID		ENSG00000038002
Uniprot IDs		P20933
PDB IDs		1APY 1APZ
Enriched GO Terms of Interacting Partners?		Enterobactin Binding Exogenous Protein Binding Cellular Response To Calcium Ion Starvation Insulin-like Growth Factor Receptor Activity Response To Tetrachloromethane Toxic Substance Binding Negative Regulation Of Mitochondrial Depolarization Insulin-like Growth Factor II Binding Insulin-like Growth Factor Binding Clathrin Coat Retromer Complex Binding Nuclear Envelope Lumen Trans-Golgi Network Transport Vesicle Regulation Of Mitochondrial Depolarization Retinoic Acid Binding D-mannose Binding Antioxidant Activity Oxygen Binding Fatty Acid Binding G-protein Alpha-subunit Binding Insulin-like Growth Factor Receptor Signaling Pathway Host-mediated Activation Of Viral Process Phosphoprotein Binding Pyridoxal Phosphate Binding Regulation Of Membrane Depolarization Copper Ion Binding Animal Organ Regeneration Structural Constituent Of Skin Epidermis
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