DLX4

Description		distal-less homeobox 4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Embryonic Skeletal System Development
Pathways
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Blood urea nitrogen levels ( 29403010) Cognitive decline rate in late mild cognitive impairment ( 26252872) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701) Serum alkaline phosphatase levels ( 29403010 33339817 33547301)
Interacting Genes		3 interacting genes: DNMT3L LSM3 MAGED1
Entrez ID		1748
HPRD ID		03553
Ensembl ID		ENSG00000108813
Uniprot IDs		Q92988
PDB IDs
Enriched GO Terms of Interacting Partners?		Lsm2-8 Complex U6 SnRNP Lsm1-7-Pat1 Complex U6 SnRNA 3'-end Binding Chorionic Trophoblast Cell Differentiation Autosome Genomic Imprinting Epigenetic Programing Of Female Pronucleus Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Negative Regulation Of Heterochromatin Formation Regulation Of Heterochromatin Formation P-body Assembly Transposable Element Silencing By PiRNA-mediated DNA Methylation Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation ESC/E(Z) Complex Epigenetic Programming In The Zygotic Pronuclei Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Precatalytic Spliceosome Regulatory NcRNA-mediated Heterochromatin Formation Transposable Element Silencing By Heterochromatin Formation Genomic Imprinting Catalytic Complex Regulation Of Chromatin Organization Male Meiosis I Positive Regulation Of Morphogenesis Of An Epithelium Regulation Of Kidney Development U4/U6 X U5 Tri-snRNP Complex Epigenetic Programming Of Gene Expression Transposable Element Silencing Meiosis I DNA Methylation-dependent Constitutive Heterochromatin Formation Placenta Development Negative Regulation Of Protein Localization To Nucleus U2-type Precatalytic Spliceosome Male Meiotic Nuclear Division Condensed Nuclear Chromosome Heterochromatin Regulation Of Morphogenesis Of A Branching Structure Constitutive Heterochromatin Formation
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