DKC1

Gene Name		dyskeratosis congenita 1, dyskerin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Cytoplasm Cajal Body
	Molecular Function	Telomerase Activity RNA Binding Protein Binding Pseudouridine Synthase Activity Poly(A) RNA Binding
	Biological Process	Telomere Maintenance Pseudouridine Synthesis RRNA Processing RNA Processing Telomere Maintenance Via Telomerase Cell Proliferation
Pathways		Telomere Maintenance Chromosome Maintenance Extension of Telomeres Telomere Extension By Telomerase
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: CSNK2A1 EEF1G EIF3F ERG LYPLA2 MAPK6 RUVBL1 SHQ1 SSR1 TERC
Entrez ID		1736
HPRD ID		02129
Ensembl ID		ENSG00000130826
Uniprot IDs		O60832
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Protein Metabolic Process Negative Regulation Of Potassium Ion Export Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of RRNA Processing Regulation Of Heart Rate By Hormone Protein Metabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Ribosome Biogenesis Translation Ribonucleoprotein Complex Assembly
Tagcloud ?		aneuploidy aplastic attrition circumstances complexly congenita constitutional cryptic delineated destabilize dyskeratosis enforcing etiologic helpful mucocutaneous multiorgan oncogenesis prominent recessive regenerative revision shelterin shorten stereotypical subtle telomere telomeropathy terc tert