ASXL1

Gene Name		additional sex combs like transcriptional regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin PR-DUB Complex Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Response To Retinoic Acid Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Monoubiquitinated Histone H2A Deubiquitination Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Bone Development
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: APP HIST1H1C SRPK1 STAT3
Entrez ID		171023
HPRD ID		16516
Ensembl ID		ENSG00000171456
Uniprot IDs		Q498B9 Q8IXJ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Feeding Behavior Regulation Of Multicellular Organism Growth Sexual Reproduction Synaptic Growth At Neuromuscular Junction Reproduction DNA Packaging Intracellular Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Reproductive Process Defense Response Collateral Sprouting Axon Midline Choice Point Recognition DNA Conformation Change Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Nucleosome Positioning Axon Choice Point Recognition Negative Regulation Of Cell Development Negative Regulation Of Glycolytic Process Neuron Remodeling Sperm Chromatin Condensation Radial Glial Cell Differentiation Cell Development Phosphorylation MRNA Processing Interleukin-6-mediated Signaling Pathway MRNA Metabolic Process Cellular Copper Ion Homeostasis Viral Process RNA Processing JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Positive Regulation Of Viral Genome Replication Behavior Copper Ion Homeostasis Suckling Behavior Regulation Of Growth Growth Hormone Receptor Signaling Pathway Temperature Homeostasis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cellular Response To Growth Hormone Stimulus Cellular Response To Interleukin-6 Regulation Of Glycolytic Process Positive Regulation Of Notch Signaling Pathway Eating Behavior Spermatid Nucleus Differentiation Neuron Maturation Negative Regulation Of Neuron Migration MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity
Tagcloud ?		abstract advancements ascribed attitude azacitidine challenging changing choices conditioning curative decitabine feasible haploidentical hematologists hypomethylating idh2 incurable optimize overview profoundly renders sf3b1 sibling spite stratify tet2 transplant video wider