DDC

Gene Name		dopa decarboxylase (aromatic L-amino acid decarboxylase)
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Gene Ontology Annotations	Cellular Component	Cytosol Synaptic Vesicle Axon Neuronal Cell Body Extracellular Vesicular Exosome
	Molecular Function	Aromatic-L-amino-acid Decarboxylase Activity Protein Binding Amino Acid Binding Enzyme Binding Protein Domain Specific Binding Pyridoxal Phosphate Binding L-dopa Decarboxylase Activity
	Biological Process	Cellular Amino Acid Metabolic Process Circadian Rhythm Multicellular Organismal Aging Synaptic Vesicle Amine Transport Isoquinoline Alkaloid Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Drug Dopamine Biosynthetic Process Catecholamine Biosynthetic Process Serotonin Biosynthetic Process Small Molecule Metabolic Process Indolalkylamine Biosynthetic Process Response To Pyrethroid Phytoalexin Metabolic Process Cellular Response To Alkaloid Cellular Response To Growth Factor Stimulus
Pathways		Amine-derived hormones Serotonin and melatonin biosynthesis Catecholamine biosynthesis Metabolism of amino acids and derivatives
Drugs		Pyridoxal Phosphate Carbidopa
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23512250 19684603) Malaria ( 19465909)
Protein-protein Interactions		3 interactors: AR ATF6 RELA
Entrez ID		1644
HPRD ID		00145
Ensembl ID		ENSG00000132437
Uniprot IDs		P20711 Q53Y41
PDB IDs		3RBF 3RBL 3RCH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Integrin Biosynthetic Process Acetaldehyde Metabolic Process Positive Regulation Of Transcription, DNA-templated Intracellular Receptor Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Schwann Cell Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Integrin Biosynthetic Process Regulation Of Schwann Cell Differentiation Response To Cobalamin Regulation Of Integrin Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of MiRNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Transcription, DNA-templated Cellular Response To Nicotine Positive Regulation Of Interleukin-12 Biosynthetic Process RNA Biosynthetic Process Response To Steroid Hormone Positive Regulation Of Transcription From RNA Polymerase III Promoter Response To Organic Substance Gland Development Positive Regulation Of Cellular Metabolic Process Regulation Of MiRNA Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Response To Muramyl Dipeptide Response To UV-B Membrane Protein Intracellular Domain Proteolysis RNA Metabolic Process Regulation Of Transcription From RNA Polymerase III Promoter Positive Regulation Of Metabolic Process Gene Expression Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Interleukin-6 Positive Regulation Of Chondrocyte Differentiation
Tagcloud ?		accelerated acetaldehyde belief blocker clonidine compartimentalization confirmation contrary da depend deprenyl elicit enhancers exceptions exists gbr mao metabolite mk mpp mptp nicotine offers produces rule sharp striatal striatum uneffective