SDE2

Description		spliceosome associated SDE2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck
	Molecular Function	DNA Binding Damaged DNA Binding RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Endonucleolytic Cleavage Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) DNA Replication MRNA Processing RNA Splicing Protein Processing Protein Ubiquitination Mitotic G1 DNA Damage Checkpoint Signaling Cellular Response To UV Ribosome Biogenesis MRNA Cis Splicing, Via Spliceosome Cell Division
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: DNAH14
Interacting Genes		2 interacting genes: OGT PCNA
Entrez ID		163859
HPRD ID		08180
Ensembl ID		ENSG00000143751
Uniprot IDs		Q6IQ49
PDB IDs		6QDV 7N99 8C6J 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		PCNA Complex Replisome Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Deoxyribonuclease Activity PCNA-p21 Complex DNA Polymerase Processivity Factor Activity Rhythmic Process Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Leading Strand Elongation Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Protein O-acetylglucosaminyltransferase Activity MutLalpha Complex Binding Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of DNA-directed DNA Polymerase Activity Regulation Of Transcription By Glucose Estrous Cycle NSL Complex Nuclear Lamina DNA Strand Elongation Involved In DNA Replication Base-excision Repair, Gap-filling Minus-end-directed Microtubule Motor Activity DNA Strand Elongation Nuclear Replication Fork Response To L-glutamate Ovulation Cycle Acetylglucosaminyltransferase Activity Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Response To Hormone DNA Polymerase Binding Sin3-type Complex Translesion Synthesis Histone Acetyltransferase Complex Negative Regulation Of Stem Cell Population Maintenance Replication Fork Liver Regeneration Mismatch Repair Histone Acetyltransferase Binding Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Dynein Light Intermediate Chain Binding Regulation Of Necroptotic Process 9+2 Motile Cilium Replication Fork Processing
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