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CLEC14A

Description C-type lectin domain containing 14A
Image No pdb structure
GO Annotations Cellular Component
  • External Side Of Plasma Membrane
  • Membrane
  • Extracellular Matrix
Molecular Function
  • Protein Binding
  • Carbohydrate Binding
  • Extracellular Matrix Binding
  • Extracellular Matrix Protein Binding
Biological Process
  • Lymphangiogenesis
  • Sprouting Angiogenesis
  • Cell Migration Involved In Sprouting Angiogenesis
  • Cell Migration
  • Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
  • Vascular Endothelial Growth Factor Receptor-3 Signaling Pathway
Pathways
Drugs
  • Resveratrol
Diseases
GWAS
  • Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
  • Two-hour glucose ( 34059833)
  • Type 2 diabetes ( 30297969 32499647)
  • Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes 13 interacting genes: ATP6V0C CLDN19 CLDN4 CYB561D2 EMD LHFPL5 MALL MGST2 MS4A1 PMP22 TMEM243 TSPAN2 VAMP3
Entrez ID 161198
HPRD ID 10711
Ensembl ID ENSG00000176435
Uniprot IDs Q86T13
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Membrane
  • Paracellular Transport
  • Myelination
  • Axon Ensheathment
  • Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
  • Bicellular Tight Junction
  • Plasma Membrane
  • Tight Junction
  • Renal Absorption
  • Bicellular Tight Junction Assembly
  • Tight Junction Organization
  • Tight Junction Assembly
  • TMEM240-body
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