PPM1K

Gene Name		protein phosphatase, Mg2+/Mn2+ dependent, 1K
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Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix
	Molecular Function	Protein Serine/threonine Phosphatase Activity Metal Ion Binding
	Biological Process	Protein Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Conduct disorder (interaction) ( 18846501) Metabolite levels ( 22286219 22916037)
Protein-protein Interactions		2 interactors: BIRC2 MYB
Entrez ID		152926
HPRD ID		15167
Ensembl ID		ENSG00000163644
Uniprot IDs		Q8N3J5
PDB IDs		2IQ1 4DA1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Monoubiquitination Positive Regulation Of Protein K48-linked Ubiquitination Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Regulation Of Protein Monoubiquitination Regulation Of Protein K63-linked Ubiquitination Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Immune Response Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Negative Regulation Of Necroptotic Process Positive Regulation Of Histone H3-K9 Methylation Negative Regulation Of Necrotic Cell Death Regulation Of RIG-I Signaling Pathway Regulation Of Necroptotic Process Positive Regulation Of Histone H3-K4 Methylation Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Regulation Of Necrotic Cell Death Regulation Of Histone H3-K4 Methylation Cellular Response To Interleukin-6 Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of T-helper Cell Differentiation Necroptotic Process Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Response To Interleukin-6 Positive Regulation Of Protein Metabolic Process Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of T-helper Cell Differentiation Regulation Of Immune System Process Positive Regulation Of Histone Methylation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Toll-like Receptor Signaling Pathway NIK/NF-kappaB Signaling Programmed Necrotic Cell Death Embryonic Digestive Tract Development Necrotic Cell Death Positive Regulation Of Alpha-beta T Cell Differentiation Regulation Of Cell Differentiation Regulation Of Histone Methylation Thymus Development Cellular Component Disassembly Involved In Execution Phase Of Apoptosis TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Histone Modification Execution Phase Of Apoptosis Toll-like Receptor 4 Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Defense Response To Virus
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