FGD5

Gene Name		FYVE, RhoGEF and PH domain containing 5
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Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytoskeleton Lamellipodium Ruffle Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Rho GTPase Activity Regulation Of Cdc42 GTPase Activity Positive Regulation Of GTPase Activity Filopodium Assembly
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: JMJD6 SUV39H1
Entrez ID		152273
HPRD ID		13322
Ensembl ID		ENSG00000154783
Uniprot IDs		Q6ZNL6
PDB IDs		3MPX
Enriched GO Terms of Interacting Partners?		Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine Modification Histone Modification Histone H3-K9 Dimethylation Recognition Of Apoptotic Cell Chromatin Modification Histone H3-K9 Trimethylation Chromatin Organization Peptidyl-lysine Dimethylation Chromatin Silencing At RDNA Phagocytosis, Recognition Peptidyl-amino Acid Modification Negative Regulation Of Circadian Rhythm Histone H3-K9 Methylation Chromosome Organization Peptidyl-lysine Trimethylation Protein Hydroxylation Macrophage Activation Apoptotic Cell Clearance Chromatin Silencing Histone Demethylation Histone H3-K9 Modification Protein Demethylation Erythrocyte Development Sprouting Angiogenesis Demethylation Regulation Of MRNA Splicing, Via Spliceosome T Cell Differentiation In Thymus Negative Regulation Of Gene Expression, Epigenetic Regulation Of MRNA Processing Histone Lysine Methylation Regulation Of Circadian Rhythm Peptidyl-lysine Methylation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of RNA Splicing Gene Silencing Erythrocyte Differentiation Cellular Response To Oxygen Levels Transcription, DNA-templated Erythrocyte Homeostasis Histone Methylation RNA Biosynthetic Process Cell Recognition RRNA Processing RRNA Metabolic Process Myeloid Cell Homeostasis T Cell Differentiation
Tagcloud ?		adc aldh1l1 ankrd28 bhlhe40 cggbp1 ctdspl ephb1 fbln2 foxp1 gnai2 gorasp1 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a