GDF7

Description		growth differentiation factor 7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Growth Factor Activity Identical Protein Binding
	Biological Process	Axon Guidance Positive Regulation Of Gene Expression Roof Plate Formation Spinal Cord Association Neuron Differentiation Neural Tube Development Gland Morphogenesis BMP Signaling Pathway Epithelial Cell Differentiation Midbrain Development Activin Receptor Signaling Pathway Cell Fate Commitment Positive Regulation Of Neuron Differentiation Positive Regulation Of DNA-templated Transcription Reproductive Structure Development Branching Morphogenesis Of An Epithelial Tube Forebrain Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Morphogenesis Of An Epithelial Fold Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Tendon Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Abdominal aortic aneurysm ( 27899403) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Esophageal adenocarcinoma ( 27527254) Haemorrhoidal disease ( 33888516) Pelvic organ prolapse ( 32184442) Pulse pressure ( 27841878) Response to statin therapy ( 20339536)
Interacting Genes		1 interacting genes: BMP7
Entrez ID		151449
HPRD ID		06873
Ensembl ID		ENSG00000143869
Uniprot IDs		Q75RY1 Q7Z4P5
PDB IDs
Enriched GO Terms of Interacting Partners?		Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Negative Regulation Of Glomerular Mesangial Cell Proliferation Allantois Development Positive Regulation Of Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Monocyte Aggregation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Neural Fold Elevation Formation Nephrogenic Mesenchyme Morphogenesis Metanephric Mesenchyme Morphogenesis Positive Regulation Of Hyaluranon Cable Assembly Negative Regulation Of Prostatic Bud Formation Regulation Of Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Regulation Of Removal Of Superoxide Radicals Negative Regulation Of Somatic Stem Cell Population Maintenance Regulation Of Branching Involved In Prostate Gland Morphogenesis Regulation Of Prostatic Bud Formation Negative Regulation Of Cell Proliferation Involved In Kidney Development Ameloblast Differentiation Cell Proliferation Involved In Metanephros Development Pericardium Morphogenesis Chorio-allantoic Fusion Branching Involved In Salivary Gland Morphogenesis Mesenchymal Cell Apoptotic Process Embryonic Skeletal Joint Morphogenesis Cell Proliferation Involved In Kidney Development Regulation Of Glomerular Mesangial Cell Proliferation Regulation Of Response To Reactive Oxygen Species Negative Regulation Of Mesenchymal Cell Apoptotic Process Regulation Of Somatic Stem Cell Population Maintenance Leukocyte Aggregation Salivary Gland Morphogenesis Endocardial Cushion Formation BMP Receptor Binding Positive Regulation Of Heterotypic Cell-cell Adhesion Mesonephros Development Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Dendrite Development Embryonic Camera-type Eye Morphogenesis Pharyngeal System Development Hindbrain Development Regulation Of Cellular Response To Oxidative Stress Morphogenesis Of An Epithelial Sheet Heart Trabecula Morphogenesis Regulation Of Brown Fat Cell Differentiation Apoptotic Process Involved In Morphogenesis Negative Regulation Of Stem Cell Population Maintenance Mesenchymal Cell Proliferation Embryonic Eye Morphogenesis Camera-type Eye Morphogenesis
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