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NFAM1
Description
NFAT activating protein with ITAM motif 1
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Azurophil Granule Membrane
Membrane Raft
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
Biological Process
Positive Regulation Of Cytokine Production
Inflammatory Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
B Cell Differentiation
Calcineurin-NFAT Signaling Cascade
Intracellular Signal Transduction
Regulation Of B Cell Differentiation
B Cell Receptor Signaling Pathway
Positive Regulation Of B Cell Receptor Signaling Pathway
Pathways
Neutrophil degranulation
Drugs
Diseases
GWAS
Chronotype (
30696823
)
Machado-Joseph disease (age at onset) (
32205469
)
Refractive error (
32231278
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Novel Interacting Genes
1 novel interacting genes:
CHADL
Interacting Genes
6 interacting genes:
BCL11A
CFTR
MAL2
SYK
TCF4
ZAP70
Entrez ID
150372
HPRD ID
16380
Ensembl ID
ENSG00000235568
Uniprot IDs
Q8NET5
PDB IDs
Enriched GO Terms of Interacting Partners
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Beta Selection
Positive Regulation Of Developmental Process
Regulation Of Developmental Process
T Cell Selection
Positive Regulation Of Alpha-beta T Cell Proliferation
T Cell Receptor Complex
Regulation Of Multicellular Organismal Development
Regulation Of Cell Differentiation
Non-membrane Spanning Protein Tyrosine Kinase Activity
Positive Regulation Of Alpha-beta T Cell Differentiation
Phosphotyrosine Residue Binding
Positive Regulation Of Calcium-mediated Signaling
Positive Regulation Of Cell Differentiation
Leukocyte Cell-cell Adhesion
Peptidyl-tyrosine Phosphorylation
Intracellularly ATP-gated Chloride Channel Activity
Positive Regulation Of Voltage-gated Chloride Channel Activity
Sec61 Translocon Complex Binding
Interleukin-15 Receptor Binding
Positive Regulation Of Interleukin-3 Production
Positive Regulation Of Alpha-beta T Cell Activation
Negative Regulation Of Branching Morphogenesis Of A Nerve
Negative Regulation Of Neuron Remodeling
Positive Regulation Of Exocytosis
Positive Regulation Of Cell Development
Regulation Of Calcium-mediated Signaling
Positive Regulation Of Anion Channel Activity
Positive Regulation Of T Cell Proliferation
T Cell Aggregation
Transcription Regulatory Region Nucleic Acid Binding
Positive Regulation Of Monoatomic Anion Transport
Positive Regulation Of T Cell Differentiation
Regulation Of Alpha-beta T Cell Activation
Serotonin Secretion By Platelet
Protein Tyrosine Kinase Activity
Beta-catenin-TCF7L2 Complex
Negative Regulation Of Protein Homooligomerization
Negative Regulation Of Neuron Maturation
Collagen Fibril Binding
Negative Regulation Of Collagen Fibril Organization
Positive Regulation Of Enamel Mineralization
T Cell Differentiation
Serotonin Secretion
Positive Regulation Of Lymphocyte Proliferation
Antigen Receptor-mediated Signaling Pathway
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Lymphocyte Differentiation
Positive Regulation Of Mononuclear Cell Proliferation
B Cell Receptor Complex
TFIIB-class Transcription Factor Binding
Tagcloud
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