CTNNA2

Gene Name		catenin (cadherin-associated protein), alpha 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Adherens Junction Cell-cell Adherens Junction Actin Cytoskeleton Basolateral Plasma Membrane Lamellipodium Axon
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Axonogenesis Single Organismal Cell-cell Adhesion Radial Glia Guided Migration Of Purkinje Cell Muscle Cell Differentiation Dendrite Morphogenesis Brain Morphogenesis Positive Regulation Of Muscle Cell Differentiation Regulation Of Synapse Structural Plasticity Prepulse Inhibition
Pathways		CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Bipolar disorder ( 19416921) Protein quantitative trait loci ( 18464913)
Protein-protein Interactions		2 interactors: CTNNBIP1 PTPN14
Entrez ID		1496
HPRD ID		00228
Ensembl ID		ENSG00000066032
Uniprot IDs		P26232 Q49AD3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Monocyte Differentiation Negative Regulation Of Cell Proliferation Lymphangiogenesis Lymph Vessel Morphogenesis Regulation Of Monocyte Differentiation Regulation Of DNA-templated Transcription, Initiation Lymph Vessel Development Regulation Of Protein Export From Nucleus Regulation Of Vascular Permeability Negative Regulation Of Stem Cell Proliferation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of DNA Binding Regulation Of Cell Proliferation Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Myeloid Leukocyte Differentiation Negative Regulation Of Protein Binding Branching Involved In Ureteric Bud Morphogenesis Ureteric Bud Morphogenesis Positive Regulation Of Osteoblast Differentiation Acute Inflammatory Response Positive Regulation Of Myeloid Cell Differentiation Nephron Morphogenesis Renal Tubule Morphogenesis Regulation Of DNA Binding Positive Regulation Of Ossification Renal Tubule Development Negative Regulation Of Binding Regulation Of Smooth Muscle Cell Proliferation Kidney Morphogenesis Regulation Of Myeloid Leukocyte Differentiation Regulation Of Stem Cell Proliferation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Anatomical Structure Morphogenesis Mesonephros Development Regulation Of Osteoblast Differentiation Negative Regulation Of Protein Complex Assembly Nephron Development Regulation Of Protein Binding Kidney Epithelium Development Peptidyl-tyrosine Dephosphorylation Regulation Of Myeloid Cell Differentiation
Tagcloud ?		adherens anoikis arid1a cdh1 clustered complexity driver escape gli3 guided highlights hotspots illustrate integrative junction landscape muc6 multidimensional mutational organoid personalized perturbations perturbed players rhoa rnf43 road signatures top