CTNNA2

Description		catenin alpha 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Postsynaptic Density Actin Cytoskeleton Membrane Basolateral Plasma Membrane Catenin Complex Lamellipodium Axon Cell Projection Anchoring Junction Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Presynaptic Active Zone Cytoplasmic Component Extrinsic Component Of Presynaptic Membrane Extrinsic Component Of Postsynaptic Membrane Postsynaptic Density, Intracellular Component
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Beta-catenin Binding Identical Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Cytoskeleton Organization Cell Adhesion Axonogenesis Regulation Of Neuron Projection Development Cell Migration Radial Glia Guided Migration Of Purkinje Cell Cell Differentiation Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Dendrite Morphogenesis Brain Morphogenesis Regulation Of Synapse Structural Plasticity Prepulse Inhibition Cell-cell Adhesion Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Neuron Migration
Pathways		Myogenesis Myogenesis
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alcohol consumption ( 28937693) Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767) Alzheimer's disease (cognitive decline) ( 23535033) Bipolar disorder ( 19416921) Body mass index ( 25673413 26426971) Bone mineral density (femoral neck) ( 26911590) Breast cancer ( 25824743) Cerebral microbleeds ( 31209788) Cerebrospinal fluid clusterin levels ( 26545630) Cleft palate ( 30452639) Cognitive function ( 25644384) Contrast sensitivity ( 24152035) Cooked vegetable consumption ( 32066663) Femur bone mineral density x serum urate levels interaction ( 34046847) Fish- and plant-related diet ( 32066663) Gut microbiota relative abundance (Bacteroides) ( 33208821) Heel bone mineral density x serum urate levels interaction ( 34046847) LDL cholesterol levels in HIV infection ( 33109212) Mild influenza (H1N1) infection ( 26379185) Multisite chronic pain ( 31194737 33830993) Orthostatic hypotension ( 24124408) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Protein quantitative trait loci ( 18464913) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to cytadine analogues (cytosine arabinoside) ( 24483146) Response to lurasidone in schizophrenia ( 29730043) Schizophrenia (MTAG) ( 32107650) Survival in pancreatic cancer ( 28470677)
Novel Interacting Genes		1 novel interacting genes: TOMM70
Interacting Genes		3 interacting genes: CCDC88A CTNNBIP1 PTPN14
Entrez ID		1496
HPRD ID		00228
Ensembl ID		ENSG00000066032
Uniprot IDs		F6KRI5 P26232 Q49AD3
PDB IDs		6DUW
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization Maintenance Of Protein Location In Plasma Membrane Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Beta-catenin-ICAT Complex
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