SIX5

Gene Name		SIX homeobox 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Sequence-specific DNA Binding
	Biological Process	Lens Development In Camera-type Eye Transcription, DNA-templated Spermatid Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Skeletal Muscle Satellite Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: ATXN1 EYA3 HMGB1
Entrez ID		147912
HPRD ID		09024
Ensembl ID		ENSG00000177045
Uniprot IDs		Q8N196
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apoptotic Cell Clearance Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Base-excision Repair, DNA Ligation Histone Dephosphorylation Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Response To Radiation DNA Ligation Involved In DNA Repair Positive Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Cell Clearance Negative Regulation Of Phagocytosis DNA Ligation Dendritic Cell Chemotaxis DNA Repair Chromatin Modification Apoptotic DNA Fragmentation Chromatin Organization Regulation Of DNA-templated Transcription, Initiation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Metabolic Process Dendritic Cell Migration Negative Regulation Of Transcription From RNA Polymerase II Promoter Myeloid Dendritic Cell Activation Positive Chemotaxis V(D)J Recombination Cellular Response To DNA Damage Stimulus Apoptotic Nuclear Changes Inflammatory Response To Antigenic Stimulus DNA Topological Change Positive Regulation Of DNA Repair Positive Regulation Of DNA Binding Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Metabolic Process Negative Regulation Of Endocytosis Regulation Of Transcription, DNA-templated Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Lung Alveolus Development Regulation Of RNA Metabolic Process Neurological System Process Nucleobase-containing Compound Metabolic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Visual Learning
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