SPC24

Gene Name		SPC24, NDC80 kinetochore complex component
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Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleus Nucleolus Cytosol Ndc80 Complex
	Molecular Function	Protein Binding
	Biological Process	Mitotic Cell Cycle Mitotic Nuclear Division Cell Division
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		HDL cholesterol ( 23505323)
Protein-protein Interactions		5 interactors: APP PSEN2 SKA1 SKA2 SKA3
Entrez ID		147841
HPRD ID		15464
Ensembl ID
Uniprot IDs		B4DZZ7 Q8NBT2
PDB IDs		2VE7 3IZ0
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Chromosome Segregation Regulation Of Epidermal Growth Factor-activated Receptor Activity Endoplasmic Reticulum Calcium Ion Homeostasis Mitotic Nuclear Division Cell Division Regulation Of Protein Tyrosine Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cytoskeleton Organization Regulation Of ERBB Signaling Pathway Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Receptor Activity Mitotic Cell Cycle Notch Signaling Pathway Regulation Of Protein Binding Synaptic Growth At Neuromuscular Junction Regulation Of Organelle Organization Collateral Sprouting In Absence Of Injury Regulation Of Peptidyl-tyrosine Phosphorylation Cell Cycle Process Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Learning Or Memory Axon Choice Point Recognition Cognition Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cell Cycle Neuron Remodeling Amyloid Precursor Protein Catabolic Process Axon Guidance Regulation Of Cellular Amino Acid Metabolic Process Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Forebrain Development Cellular Ion Homeostasis Single-organism Behavior Membrane Protein Intracellular Domain Proteolysis Metal Ion Homeostasis Cellular Copper Ion Homeostasis Membrane Protein Ectodomain Proteolysis Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Cellular Ketone Metabolic Process
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