RDH12

Gene Name		retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Photoreceptor Inner Segment Membrane
	Molecular Function	Retinol Dehydrogenase Activity Protein Binding
	Biological Process	Retinoid Metabolic Process Visual Perception Phototransduction, Visible Light Retinol Metabolic Process Photoreceptor Cell Maintenance Oxidation-reduction Process
Pathways		Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Retinoid cycle disease events Diseases associated with visual transduction
Drugs		Vitamin A
Diseases
GWAS
Protein-protein Interactions		3 interactors: BUB1 MAP1LC3A RBPMS
Entrez ID		145226
HPRD ID		10585
Ensembl ID		ENSG00000139988
Uniprot IDs		Q96NR8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Sister Chromatid Cohesion Regulation Of SMAD Protein Import Into Nucleus Cellular Response To Nitrogen Starvation Nucleophagy Mitochondrion Degradation Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Organelle Disassembly Negative Regulation Of Chromosome Segregation Autophagic Vacuole Assembly Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Pathway-restricted SMAD Protein Phosphorylation Macroautophagy Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Signal Transduction
Tagcloud ?		abca4 allelic audiogram bbs1 c2orf71 cerkl crb1 decisive deepen denaturing dhplc discern dystrophies electrophysiology fundus homozygosity hrm intrafamilial melt mlpa monoallelic ngs pde6b pedigrees sanger sscp tulp1 ush2a