RFLNA

Description		refilin A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Actin Filament Bundle
	Molecular Function	Protein Binding Filamin Binding
	Biological Process	Skeletal System Morphogenesis Regulation Of Chondrocyte Development Negative Regulation Of Chondrocyte Development Actin Filament Bundle Organization Negative Regulation Of Bone Mineralization Involved In Bone Maturation
Pathways
Drugs
Diseases
GWAS		Hallux valgus ( 32131869) Optic cup area ( 31798171) Osteoarthrosis (time to event) ( 32589924) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
Novel Interacting Genes		1 novel interacting genes: MTRFR
Interacting Genes		3 interacting genes: FBXW7 FDFT1 FLNA
Entrez ID		144347
HPRD ID		14066
Ensembl ID		ENSG00000178882
Uniprot IDs		Q6ZTI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Squalene Synthase [NAD(P)H] Activity Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups Farnesyl Diphosphate Metabolic Process Glycoprotein Ib-IX-V Complex Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Protein Localization To Bicellular Tight Junction Protein Stabilization Fc-gamma Receptor I Complex Binding Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Formation Of Radial Glial Scaffolds Tubulin Deacetylation Negative Regulation Of Protein Catabolic Process Myb Complex Establishment Of Sertoli Cell Barrier Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Negative Regulation Of Hepatocyte Proliferation Ubiquitin Recycling Phosphothreonine Residue Binding Negative Regulation Of SREBP Signaling Pathway Negative Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Osteoclast Development Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Translation Release Factor Activity Translation Release Factor Activity, Codon Specific Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Blood Coagulation, Intrinsic Pathway Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Establishment Of Protein Localization Ubiquitin-protein Transferase Activator Activity Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Osteoclast Development Negative Regulation Of Transcription By RNA Polymerase I Regulation Of SREBP Signaling Pathway Positive Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Platelet Activation Regulation Of Protein Catabolic Process Protein Deacetylation Regulation Of Protein Stability Negative Regulation Of Catabolic Process Translational Termination Actin Crosslink Formation Negative Regulation Of Triglyceride Metabolic Process Ribosomal Large Subunit Binding Positive Regulation Of Neuron Migration Regulation Of Hepatocyte Proliferation Apical Dendrite Sertoli Cell Development Protein Localization To Cell-cell Junction Regulation Of Triglyceride Biosynthetic Process
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