ALG10B

Gene Name		ALG10B, alpha-1,2-glucosyltransferase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transferase Activity, Transferring Hexosyl Groups
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Defective ALG11 causes ALG11-CDG (CDG-1p) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS		Drug-induced liver injury (flucloxacillin) ( 19483685)
Protein-protein Interactions		1 interactors: KCNH2
Entrez ID		144245
HPRD ID		11923
Ensembl ID
Uniprot IDs		Q5I7T1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Potassium Ion Export Regulation Of Heart Rate By Hormone Peptidyl-histidine Phosphorylation Regulation Of Heart Rate By Chemical Signal Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Potassium Ion Export Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Negative Regulation Of Potassium Ion Transmembrane Transport Potassium Ion Homeostasis Phosphorelay Signal Transduction System Positive Regulation Of Potassium Ion Transmembrane Transport Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Potassium Ion Transport Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Potassium Ion Transport Membrane Depolarization During Action Potential Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Negative Regulation Of Ion Transmembrane Transport Cardiac Muscle Contraction Negative Regulation Of Transmembrane Transport Cellular Response To Drug Regulation Of Potassium Ion Transport Heart Contraction Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Negative Regulation Of Ion Transport Membrane Depolarization Regulation Of Muscle Contraction Regulation Of Heart Contraction Potassium Ion Transmembrane Transport Positive Regulation Of Ion Transport Potassium Ion Transport Muscle Contraction Muscle System Process Regulation Of Membrane Potential Signal Transduction By Phosphorylation Blood Circulation Negative Regulation Of Transport Regulation Of Actin Filament-based Process
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