CRYGS

Description		crystallin gamma S
Image
GO Annotations	Cellular Component
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Morphogenesis Of An Epithelium Lens Development In Camera-type Eye Visual Perception
Pathways
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Glaucoma (primary open-angle) ( 29449654) Illicit drug use ( 23942779) Open-angle glaucoma and vertical cup-disc ratio ( 29449654)
Interacting Genes		4 interacting genes: CRYAB POT1 TERF2IP TINF2
Entrez ID		1427
HPRD ID		00439
Ensembl ID		ENSG00000213139
Uniprot IDs		A0A140CTX8 P22914
PDB IDs		1HA4 2M3T 2M3U 6FD8 6IF9 7N36 7N37 7N38 7N39 7N3A 7N3B 7NJE
Enriched GO Terms of Interacting Partners?		Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Telomere Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Telomere Organization Negative Regulation Of DNA Metabolic Process G-rich Strand Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Cellular Component Organization Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Regulation Of Chromosome Organization RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Positive Regulation Of DNA Metabolic Process Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Chromosome Organization Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Regulation Of DNA Biosynthetic Process DNA Biosynthetic Process Positive Regulation Of DNA Strand Elongation Chromosome Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Protein Localization To Chromosome DNA Metabolic Process Regulation Of Cellular Component Organization Positive Regulation Of Telomeric Loop Disassembly Regulation Of Double-strand Break Repair Perinucleolar Chromocenter Negative Regulation Of DNA Recombination At Telomere Organelle Organization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Telomeric D-loop Binding
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